Pete and Debbie are both about to turn 40, their kids hate each other, both of their businesses are failing, they're on the verge of losing their house, and their relationship is threatening to fall apart.
Pete
Paul Rudd
Debbie
Leslie Mann
Oliver
John Lithgow
Desi
Megan Fox
Sadie
Maude Apatow
Charlotte
Iris Apatow
Ronnie
Chris O'Dowd
Jason
Jason Segel
Catherine
Melissa McCarthy
Graham Parker
Graham Parker
Larry
Albert Brooks
Cat
Lena Dunham
Barb
Annie Mumolo
Barry
Robert Smigel
Jodi
Charlyne Yi
Clair
Lisa Darr
Billie Joe Armstrong
Billie Joe Armstrong
Accountant
Michael Ian Black
Flirty Hockey Player
Wyatt Russell
Charlotte's Teacher
Tom Yi
Dr. Pellegrino
Tim Bagley
Wendy
Ava Sambora
School Playdate Parent
Megan Grano
Older Pregnant Parent
D.A. Sandoval
Room Service Waiter
Derek Basco
E.R. Nurse
Nicol Paone
Disturbed Restaurant Patron (uncredited)
Lynne Alana Delaney
BBQ Guest (uncredited)
Katia Kieling
Desi's Store Pickup (uncredited)
Bill Hader
Pete's Doctor
Tom Everett
Realtor
Tatum O'Neal
Ryan Adams
Ryan Adams
Joseph
Ryan Lee
Dentist
Dan Bakkedahl
Party Guest #1 (uncredited)
Jessica Lee
Gyno Nurse
Rebekka Johnson
Room Service Waiter
Johnny Pemberton