A husband and wife struggle to keep their marriage alive until they realize they are both secretly working as assassins. Now, their respective assignments require them to kill each other.
John Smith
Brad Pitt
Jane Smith
Angelina Jolie
Eddie
Vince Vaughn
Benjamin Danz
Adam Brody
Jasmine
Kerry Washington
Father
Keith David
Martin Coleman
Chris Weitz
Suzy Coleman
Rachael Huntley
Gwen
Michelle Monaghan
Julie - Associate #1
Stephanie March
Jade - Associate #2
Jennifer Morrison
Janet - Associate #3
Theresa Barrera
Jessie - Associate #4
Perrey Reeves
Jamie - Associate #5
Melanie Tolbert
Guard - Bull
Jerry T. Adams
Marco Racin
Elijah Alexander
Louis
Hans F. Alexander
Coleman Kid #2
Lauryn Alvarez
Restaurant Patron
Burke Armstrong
P.J.
Ron Bottitta
50's Man
Earl H. Bullock
Bellboy - Bogotá
Miguel Angel Caballero
Americana Hotel Manager
Victor A. Chapa
Father's Secretary
Maree Cheatham
Eddie's Waitress
Laine Collins
Coleman Kid #1
Noah Dahl
Mom #2
Merrilee Dale
Mailman Assassin
Chris Daniels
50's Woman
Patrika Darbo
Breakfast Diner Waitress
Jennifer DeMille
Salsa Dancer #2
Tyce Diorio
Louise
Patricia Donaldson
Bodyguard #3
Sabi Dorr
Mickey
Greg Ellis
Americana Hotel Bartender
David Escobedo
Neighborhood Girl
Kaela Freeman
40's Woman
Megan Gallagher
Beauty
Amy Hathaway
Hopskotch Girl #2
Jessica Hedden
Hopscotch Girl #1
Kathrine Herzer
Boxing Sparring Partner
Nigel Hudson
Curtis
Ravil Isyanov
Party Guest
Stephanie Ittleson
Patron - Dive Bar
Mark Ivanir
Maitre'D
Benton Jennings
Investment Banker #1
Simon Kinberg
Leroy
Peter Lavin
Doorman
Deren Tadlock
Lucky
Sean Mahon
Johnson
Kevin Makely
Bill the Neighbor
Mike McCaul
Policia #2
Derek Medina
House Assassin #1
Will Moore
Policia #1
Joel Munoz
Guard #1
Mark Newsom
Policia #4
Richie Ornelas
House Assassin #2
Jordan Osher
Colombian Military Officer
Edward Padilla
Judge
Eugene C. Palmer
Policia #3
Luis Racer
Salsa Dancer #1
Liz Ramos
Watchguard
Leonard Robinson
Vocalist
Felix A. Ruiz
Bodyguard
Sam Sabbah
Bartender - Dive Bar
Kim Schioldan
Towncar Driver
Ty Sharp
Ancient Barker
Jimmy Shubert
Mom #3
Abigail Rose Solomon
Hopskotch Girl #3
Hannah Von Kanel
Mom #1
Ali Marsh
Mr. Smith's Father
Kim H. Winther
Investment Banker #2
Michael Winther
Bartender - Coleman House
Michael-John Wolfe
40's Man
Jeff Yagher
Dancer
Bryan Anthony
Dancer
Douglas Caldwell
Dancer
R.J. Durell
Dancer
Melissa Hurley
Dancer
Jacqui Landrum
Dancer
Carol Mack
Dancer
Michael Morris
Dancer
Gloria Rodriguez
Dancer
Linda Kathleen Taylor
Dancer
Anne Vardanian
Dancer
Ara Vardanian
Dancer
Luis Vasquez
Dancer
John W. Woodruff
Mr. Smith's Boss (voice) (uncredited)
Angela Bassett
Dr. Wexler - Marriage Counselor (voice) (uncredited)
William Fichtner
Security Guard (uncredited)
David Block
Swat Team Member (uncredited)
John Branch
Sebastian James (uncredited)
Julius Callahan
Assassin (uncredited)
Shilo Frontierro
Dancer (uncredited)
Lisa Gabriel
Big Bad Bathroom Dude (uncredited)
Tony Longo
Woman #3 (uncredited)
Janelle Marra
BB Gun Shooter (uncredited)
Heather Petrone
Dancer (uncredited)
Bill Viney
Swat Officer (uncredited)
Hawk Younkins
Assassin (uncredited)
Matt McColm
Algerian Assassin (uncredited)
Mo Gallini