A lab accident gives a beagle named Shoeshine some serious superpowers -- a secret that the dog eventually shares with the young boy who becomes his owner and friend.
Shoeshine / Underdog (voice)
Jason Lee
Dr. Simon Barsinister
Peter Dinklage
Dan Unger
Jim Belushi
Cad
Patrick Warburton
Jack Unger
Alex Neuberger
Molly
Taylor Momsen
Mayor
John Slattery
Polly Purebred (voice)
Amy Adams
Riff Raff (voice)
Brad Garrett
Principal
Samantha Bee
Police Chief
Timothy Crowe
Security Guard
Larry Vigus
Police Officer
Mario Mariani
Cop
Bates Wilder
Small Boy
Alexander 'Alex' Garde
Mailman (as Christopher Byrnes)
Christopher Francis Byrnes
News Stand Guy (as Joseph Siriani)
Joe Siriani
Office Worker #1
Sujoy De
Office Worker #2
Michele Proude
Geek Worker
Albert M. Chan
Hot Dog Vendor
Jon Pierce
Diana Flores
Susie Castillo
Professor
Bob Jaffe
City Worker (as Bruce Serafin)
Bruce-Robert Serafin
Passerby
Lonnie Farmer
Male School Teacher (as Tony Estrella)
Anthony Estrella
Bomb Squad Officer
Malik McMullen
Little Boy
Aaron Dorsey
Old Man
Walter Covell
Housewife
Kate Lohman
Geek with Glasses
Lewis D. Wheeler
Female Teacher
Ellen Withrow
Newscaster
John M. Deluca
Police Sergeant
Frank Ridley
College Guy
Grady Justice
College Girl
Courtney O'Reagan
Fox Collar Lady
Rebekah Aramini
Baseball Dad
Richney Fischer
Cat Burglar Police #1
Joe Stapleton
Cat Burglar Police #2
Armen Garo
News Director
Daniel Kirby
Bomb Squad Member (as Steve Kidd)
Stephen James Kidd
Mother
Rena Maliszewski
Police Secretary
Diana Shneider
SWAT Captain
Barry Blair
Bomb Squad Officer #2 (as Robert Boehm)
Bob Boehm
Bomb Squad Officer #3
Lincoln P. Sisson
Lyle
Gabriel Field
Police Artist
Harry L. Thomas
Kissing Girl
Amy Tanner
Jogger in Park
Nicole Kopka
Capitol City Security
Adam McCarthy
Capitol City Cop
Roy Souza
Capitol City Cop
Tom Paolino
Hot Dog Contestant
Scott Dittman
Referee
Ezra Buzzington
Fireman (as Chris Ciulla)
Chris Andrew Ciulla
Jay Leno
Jay Leno
Supershep 1 (voice)
Phil Morris
Supershep 2 (voice)
Michael Massee
Little Brown Dog / Supershep 3 (voice)
Cam Clarke
Bulldog / Supershep 4 (voice)
John DiMaggio
Crazy Dog (voice)
Danny Mastrogiorgio
Astronaut (voice)
Jess Harnell
Goon #1
Joe Bucaro III
Goon #2
Stuart F. Wilson
Observer (uncredited)
John Franchi
Office Worker (uncredited)
Susan Garfield
Jack Unger (voice)
Michael Tyler Henry